Description
| Catalogue Number | P00449 | ||||||||||||||||||||||
| Description | Ionic macrocyclic gadolinium complex of DOTA designed for MRI imaging. Its parametric proprieties increase contrast enhancement in MRI. Freely excreted by the kidneys and very inert biologically | ||||||||||||||||||||||
| Main Applications | Detection of brain tumor, rachis pathology, whole body pathology (including angiography), osteo-articular imaging, brain perfusion, DCE – MRI | ||||||||||||||||||||||
| Molecular characteristics |
– Macrocyclic and ionic Gd-based chelate
– Hydrodynamic size: 1 nm
– Molecular weight: 560 Da
– Recommended dose: 100 μmol/kg = 2.5 μL/g
– Relaxivities (s-1.mM-1, precision ±10%, 37°C, HSA 4%) [1]
– Quantitative techniques: ICP-AES, ICP-MS, relaxometry… |
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| Characteristics of the vial |
– Concentration: [Gd] = 40 mmol/L |
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| Storage | Need to be stored at ambient temperature in a closed vial | ||||||||||||||||||||||
| Notes | For in vitro or animal use only | ||||||||||||||||||||||
| Selected publications | 1] Unpublished Guerbet Data [2] Idee et al., Fundam Clin Pharmacol., 2006 [3] Van der Elst; ISMRM 2013 [4] Lefevre et al., Radiology 2011 [5] Ruehm et al, MRM 2000 | ||||||||||||||||||||||
